Known Issues with Adobe products on Mac OS 10.7 Lion : http://kb2.adobe.com/cps/905/cpsid_90508.html
I’m on CS5.5, so it’s not that big a deal for me. The main problem is Flash Player, which is a bit more serious: hardware acceleration, hardware mouse animation, and so on. I’m hoping Adobe puts out a patch soon — and also that they add support for Versions.
Apple is a real pain to deal with. Reading this Adobe doc feels like watching a little girl get bullied.
Also, with Rosetta gone, Warcraft III, StarCraft, SimCity 4 and the like are all history.